Mean Mule Distilling Co. DETAILS Downtown Address: 1733 Locust St., Kansas City, MO 64108 Get Directions Phone: (816) 514-1537 Visit Website Hours: 4-10pm Tue.-Thu., 4pm-12am Fri., 12pm-12am Sun. 12-7pm Sun. Distillery making American Agave spirits in the heart of the Midwest. Location & What's Nearby Places to Eat Where to Stay Attractions Entertainment Arts & Culture Shopping Sports & Recreation